For the long-term treatment of pulmonary arterial hypertension (WHO functional classes II-III) as monotherapy or in combination therapy in adult patients with:

• Primary (idiopathic and hereditary) pulmonary arterial hypertension
• Pulmonary arterial hypertension with compensated congenital uncomplicated heart defects
• Pulmonary arterial hypertension associated with connective tissue diseases

Included in the List of Essential Medicines